Anti-ITA2B Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-10-24
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K106413P
|
| 應用范圍 |
WB
|
| CAS編號 |
|
| 抗體名 |
Anti-ITA2B Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點 |
MKP1
|
| 適應物種 |
Human
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標識物 |
ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human ITA2B
|
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
