Anti-CD14 Polyclonal Antibody
- 發(fā)布日期： 2019-05-13
- 更新日期： 2025-10-24
產(chǎn)品詳請
| 產(chǎn)地 |
北京
|
| 品牌 |
Solarbio
|
| 保存條件 |
Store at -20°C. Avoid freeze / thaw cycles.
|
| 貨號 |
K101533P
|
| 應用范圍 |
WB
|
| CAS編號 |
|
| 抗體名 |
Anti-CD14 Polyclonal Antibody
|
| 克隆性 |
Polyclonal Antibody
|
| 靶點 |
CATD (light chain,Cleaved-Gly65)
|
| 適應物種 |
Human
|
| 形態(tài) |
|
| 宿主 |
Rabbit
|
| 亞型 |
IgG
|
| 標識物 |
CD14;Monocyte differentiation antigen CD14;CD14 molecule;LPS-R;Mo2
|
| 濃度 |
%
|
| 免疫原 |
A synthetic peptide of human CD14
|
Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.
